Andreas Grabrucker

FAQ About Andreas Grabrucker

• What is Andreas Grabrucker's address?

  Andreas Grabrucker is located at
  County Limerick, County Limerick, Ireland

• What is Andreas Grabrucker's job title?

  Andreas Grabrucker is a
  My research is interested in the underlying components able to modify synaptic plasticity and transmission in the Central Nervous System (CNS) in health and disease. Using a combination of biochemical, cellular, molecular and behavioral approaches, we investigate proteins of excitatory postsynapses focusing on their deregulation in neurodevelopmental and neurodegenerative disorders such as Autism Spectrum Disorders, Alzheimer’s disease and Schizophrenia. I am especially interested in the functional interaction of biometals and synaptic proteins in mechanisms such as synapse formation and maturation in health and disease. Given that dysregulation of trace metals is reported in many brain disorders, their role in the modification of synaptic function needs to be investigated in more detail. Especially since many brain disorders seem to not only have a genetic but also an environmental component triggering the disease. To investigate the role of biometals in disorders of the CNS, I use several approaches. For example, targeted manipulation of biometal levels in animal models and cells derived from human induced pluripotent stem cells is a major goal in our research. To that end, the development of novel drug carriers (i.e. Nanoparticles) and assays designed to evaluate their potency to influence synapse formation, maturation and plasticity has become an important part of my research. Bernal Institute University Of Limerick

• What industry does Andreas Grabrucker currently work in?

  Andreas Grabrucker currently works in the
  Bernal Institute University Of Limerick

• What is Andreas Grabrucker's area of expertise?

  Andreas Grabrucker specializes in
  My research is interested in the underlying components able to modify synaptic plasticity and transmission in the Central Nervous System (CNS) in health and disease. Using a combination of biochemical, cellular, molecular and behavioral approaches, we investigate proteins of excitatory postsynapses focusing on their deregulation in neurodevelopmental and neurodegenerative disorders such as Autism Spectrum Disorders, Alzheimer’s disease and Schizophrenia. I am especially interested in the functional interaction of biometals and synaptic proteins in mechanisms such as synapse formation and maturation in health and disease. Given that dysregulation of trace metals is reported in many brain disorders, their role in the modification of synaptic function needs to be investigated in more detail. Especially since many brain disorders seem to not only have a genetic but also an environmental component triggering the disease. To investigate the role of biometals in disorders of the CNS, I use several approaches. For example, targeted manipulation of biometal levels in animal models and cells derived from human induced pluripotent stem cells is a major goal in our research. To that end, the development of novel drug carriers (i.e. Nanoparticles) and assays designed to evaluate their potency to influence synapse formation, maturation and plasticity has become an important part of my research.

• Which languages does Andreas Grabrucker speak? 

  Andreas Grabrucker speaks the following languages:
  No languages available.

• Which industries has Andreas Grabrucker previously worked in?   

  Andreas Grabrucker has prior experience in the following industries:
  Universitatsklinikum Ulm , Stanford University School Of Medicine

• What is Andreas Grabrucker’s work experience?  

  Andreas Grabrucker has the following professional experience:
  Bernal Institute University Of Limerick , University Of Limerick , Universitatsklinikum Ulm , Stanford University School Of Medicine .

• How can I find Andreas Grabrucker on LinkedIn?  

  You can view Andreas Grabrucker’s
  LinkedIn profile at LinkedIn URL.

• What are Andreas Grabrucker’s work email addresses?  

  Andreas Grabrucker’s work email addresses are
  [email protected] .

• What company does Andreas Grabrucker work for?  

  Andreas Grabrucker works at
  Bernal Institute University Of Limerick