
Louise Scharf
Extensive biotech industry experience in large molecule and small molecule drug discovery and pre-clinical development. Strong record of... | San Francisco, California, United States
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Louise Scharf’s Emails ls****@br****.com
Louise Scharf’s Phone Numbers 1877868****
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Louise Scharf’s Location San Francisco, California, United States
Louise Scharf’s Expertise Extensive biotech industry experience in large molecule and small molecule drug discovery and pre-clinical development. Strong record of scientific leadership evidenced by data-driven go/no-go decisions, patents, and publications. Innovative, strategic thinker and problem-solver. Excellent communicator. Effective and thoughtful people manager promoting healthy team dynamics to drive scientific excellence and delivery of actionable results. - Championed immunology therapeutic area strategies by leveraging human genetics and ‘omics data to facilitate target identification and drug discovery. Built collaborations between Immunology Research, Computational Biology, Human Genetics, Clinical Sciences, corresponding teams at GSK, and KOLs to enable identification of differentiated drug targets in patient cohorts with high unmet medical needs. - Scientific lead on discovery, development, and successful out-licensing of therapeutic bispecific antibody asset. - Managed a group of up to 8 accomplished Ph.D.- and Master’s-level scientists responsible for target identification and validation, and pre-clinical assay development. - Led 5 cross-functional teams spanning 23andMe and GSK (30+ scientists), coordinating activities across several functional areas including Computational Biology, Statistical Genetics, Biology Research, Functional Genomics, Translational Research, and Clinical Sciences. - Provided strategic oversight of 8 drug discovery programs for the treatment of IBD, psoriasis, atopic dermatitis, asthma, severe acne, and rare disease indications. - Championed initiative to identify untapped target classes and drug modalities for revenue-generating partnerships. Aligned Biology Research, Computational Biology, Human Genetics, Business Development, and Intellectual Property team leads to develop and prioritize strategy. - Co-authored 6 patents and 21 scientific publications with >3,200 citations. - Areas of expertise include: immunology biophysics biochemistry structural biology GWAS PheWAS EnWAS RNAseq epigenetics immune diseases assay development high-throughput screening (HTS) cellular assays biophysical assays large molecule drug discovery small molecule drug discovery antibody engineering protein engineering protein chemistry. I am interested in exploring leadership roles that would leverage my experience in synthesizing insights derived from 'omics and patient datasets with molecular and cellular biology expertise to develop transformative medicines for patients.
Louise Scharf’s Current Industry Altos Labs
Louise
Scharf’s Prior Industry
The University Of Chicago
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California Institute Of Technology
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23andme
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Altos Labs
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Work Experience

Altos Labs
Director, Pharmacology
Mon Jan 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
23andme
Director - Immunology
Sat Apr 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jan 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
23andme
Sr. Scientist, 23andMe Therapeutics - Immunology
Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Sat Apr 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
23andme
Scientist II, 23andMe Therapeutics - Immunology
Fri Feb 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Mar 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
23andme
Scientist I, 23andMe Therapeutics - Antibody and Protein Engineering
Fri Jan 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Feb 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
California Institute Of Technology
Postdoctoral Fellow
Sat Jan 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Dec 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
The University Of Chicago
Doctoral Researcher
Sun Jan 01 2006 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Jan 01 2010 00:00:00 GMT+0000 (Coordinated Universal Time)