
Maxime Mahe
The use of human pluripotent stem cells offers great avenues to generate human tissues. The understanding of intestinal... | France
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Maxime Mahe’s Emails mm****@ci****.org
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Maxime Mahe’s Location France
Maxime Mahe’s Expertise The use of human pluripotent stem cells offers great avenues to generate human tissues. The understanding of intestinal development and its translation to human pluripotent stem cells, allowed the field to move forward in understanding intestinal development and gastrointestinal diseases. For the past 5 years, our lab has developed model systems of the human intestine with the endeavor to study gastrointestinal physiopathology. Using human pluripotent stem cells, we were able to generate a human intestine reassembling human intestinal features including and enteric nervous system (ENS). In addition, we were able to model GI diseases including Hirschsprung's disease. The use of iPSCs-derived organoid models represent a real opportunity to expand our knowledge into the effect of ENS on intestinal development and toward the understanding of pathophysiological processes leading to functional gastrointestinal neuropathies. In addition, our lab is also investigating forthecoming strategies that could be used to create a fully functional intestine in vitro that could be used in conjonction with microbiota and nutrients.
Maxime Mahe’s Current Industry Cincinnati Childrens Hospital Medical Center
Maxime
Mahe’s Prior Industry
Inserm
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Chu De Nantes
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Cincinnati Childrens Hospital Medical Center
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Work Experience

Cincinnati Childrens Hospital Medical Center
Adjunct Assistant Professor
Sat Apr 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Inserm
Research Assistant Professor
Sat Apr 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Cincinnati Childrens Hospital Medical Center
Research Instructor
Wed Jul 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) — Sat Apr 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Cincinnati Childrens Hospital Medical Center
Research Fellow
Sun Jan 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Jul 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Chu De Nantes
Technicien d'Etudes Cliniques
Fri Jan 01 2010 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Jan 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time)
Inserm
PhD Student
Mon Sep 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Jan 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time)