
Robert Gampe
Diversely trained and broadly skilled drug discovery research scientist. Accomplished protein X-ray crystallographer with some cryoEM training and... | 5 Bay Ridge Court, Durham, United States
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Robert Gampe’s Location 5 Bay Ridge Court, Durham, United States
Robert Gampe’s Expertise Diversely trained and broadly skilled drug discovery research scientist. Accomplished protein X-ray crystallographer with some cryoEM training and prior expertise in NMR and biophysics. Highly skilled with structure and fragment based drug design and collaboration with chemists to advance hits to candidates. Well developed skills to produce and characterize highly purified proteins for crystallization, structure determination and biophysical analysis. Recent experience with structure, synthetic design and purification of CRISPR/CAS nucleases and AAV capsids and formulation for pre-clinical research. Has significant bioanalytical experience to characterize virus products by a variety of biochemical techniques and determine transgene titers and copy number from animal tissues. Skills and knowledge to develop, qualify and validate enzyme and a wide variety of cell based assays and culture and maintain mammalian cell lines in a GxP regulated lab setting. Extensive hands on experience with X-ray and NMR applications, equipment, maintenance, installation, lab design and liquid handling automation. Capable of leading and managing structural chemistry projects and motivated to work collaboratively across matrix organized teams to define and fulfill program requirements and goals. Self starter with drive and interest to develop self and others. Recently completed a semester long Introduction to Python programming. • 15+ years of direct drug discovery project engagement and leadership on X-ray structure based programs spanning bacterial, cancer, cardiac, inflammatory, metabolic, respiratory, viral diseases • Determined, curated, communicated 285+ protein crystal structures directly aligned with program goals, needs • Worked closely,iteratively with program chemists to analyze structures and extract information that advanced the drug discovery process • Proactively contributed to 4 projects that advanced 7 candidates to clinical trials and 3 to first time in humans • 15+ years of X-Ray laboratory operational oversight, preventive maintenance,repair,safety, laboratory design,equipment installs • 15+ years of direct development and application of analytical and structural NMR methods and data generation for drug discovery programs spanning bacterial,cancer,cardiac,endocrine,immune response,metabolic diseases • Co-authored 47 peer reviewed publications,presented many talks,posters • Creative problem solver using knowledge,discussion to derive solutions when faced with problems both in and out of my area of expertise
Robert Gampe’s Current Industry Springworks Therapeutics
Robert
Gampe’s Prior Industry
The University Of Texas Health Science Center At Houston
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Abbott Laboratories
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Glaxosmithkline
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Bioagilytix Labs
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Pfizer
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Ppd
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Pairwise
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Reactive Biosciences
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Springworks Therapeutics
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Work Experience

Springworks Therapeutics
Associate Director of Structural Biology
Thu Jun 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Reactive Biosciences
Consultant - Senior Principal Scientist - Structure Based Drug Design and Chemistry
Wed Mar 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon May 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
Reactive Biosciences
Senior Principal Scientist - Structure Based Drug Design and Chemistry
Fri Apr 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Mar 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
Pairwise
Scientist - Protein Science Research and Development
Sun Aug 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Ppd
Senior Scientist - Bioanalytical Research and Development at Jaguar Gene Therapy
Sun Nov 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Aug 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Pfizer
Senior Scientist - Structural Biology - Rare Disease Research Unit
Thu Mar 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Nov 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time)
Bioagilytix Labs
Senior Scientist
Sun Jan 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Mar 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Bioagilytix Labs
Associate Scientist
Sun Nov 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Dec 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Glaxosmithkline
Research Investigator
Thu Mar 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Sep 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Glaxosmithkline
Senior Scientist
Thu May 01 1997 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Mar 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time)
Glaxosmithkline
Senior Scientist
Fri Mar 01 1991 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu May 01 1997 00:00:00 GMT+0000 (Coordinated Universal Time)
Abbott Laboratories
Scientist
Mon Oct 01 1984 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Mar 01 1991 00:00:00 GMT+0000 (Coordinated Universal Time)
The University Of Texas Health Science Center At Houston
Scientist
Thu Apr 01 1982 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Oct 01 1984 00:00:00 GMT+0000 (Coordinated Universal Time)