
Tammie Yeh
• Over 20 years of industry experience in small biotech and large pharmaceutical companies, focusing on Oncology Translational Sciences • Extensive... | Cambridge, Massachusetts, United States
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Tammie Yeh’s Location Cambridge, Massachusetts, United States
Tammie Yeh’s Expertise • Over 20 years of industry experience in small biotech and large pharmaceutical companies, focusing on Oncology Translational Sciences • Extensive background in drug discovery and development: 1) various phases, e.g. target identification, clinical candidate selection, clinical development, 2) numerous drug targets, e.g. kinases, immune-oncology regulators, epigenetic modifiers, cell death agents, 3) different modalities, e.g. small-molecules, antibodies, RNAi • Wide-ranging expertise in Translational research, from biomarker identification in the research setting to clinical assay development to analysis of clinical trial patient samples: •Readouts: phospho-protein, cytokine, single transcript, gene signature, ctDNA, TCR sequencing, immunophenotyping •Tissues: tumor, hair follicles, whole blood, bone marrow, PBMCs, skin •Platforms: IHC, flow cytometry, immunoassays, qPCR, ddPCR, nanostring, NGS • Proven track record for leading successful Phase I clinical biomarker strategies •Development and execution of clinical biomarker plans to evaluate pharmacodynamic, patient selection, surrogate response and acquired resistance biomarkers •Contribution to clinical documents (i.e. protocol, lab manual, informed consent form), development of biomarker training materials for clinical sites, and participation on study teams/Investigator meetings •Oversight of external collaborations and engagement with KEEs (Key External Experts) • Leadership of global clinical biomarker teams of 15-20 individuals • Management and scientific supervision of research associate/PhD level scientists • Mentoring of junior scientists for scientific and professional development • Strong collaborative and communication skills for working across multiple sites and functional areas in highly matrixed environments
Tammie Yeh’s Current Industry Takeda Oncology
Tammie
Yeh’s Prior Industry
Institut Pasteur
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University Of Colorado Health Sciences Centerdivision Of Medical Oncology
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Array Biopharma
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Merck
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Astrazeneca
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Takeda
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Takeda Oncology
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Work Experience

Takeda Oncology
Senior Director, Precision and Translational Medicine, Oncology and Cell Therapy
Fri Apr 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Takeda Oncology
Director, Precision and Translational Medicine, Oncology and Cell Therapy
Wed Sep 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Takeda
Director, Clinical Biomarkers Innovation and Development, Hematology/Oncology
Sun Nov 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) — Wed Sep 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Astrazeneca
Associate Director, Oncology Translational Medicine
Mon Jul 01 2013 00:00:00 GMT+0000 (Coordinated Universal Time) — Sun Nov 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time)
Merck
Oncology Biomarkers Team Lead
Tue Sep 01 2009 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jul 01 2013 00:00:00 GMT+0000 (Coordinated Universal Time)
Array Biopharma
Senior Research Scientist
Mon Jan 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Jan 01 2009 00:00:00 GMT+0000 (Coordinated Universal Time)
University Of Colorado Health Sciences Centerdivision Of Medical Oncology
Research Scientist
Sat Jan 01 2000 00:00:00 GMT+0000 (Coordinated Universal Time) — Mon Jan 01 2001 00:00:00 GMT+0000 (Coordinated Universal Time)
Institut Pasteur
Post-doctoral Fellow
Wed Jan 01 1997 00:00:00 GMT+0000 (Coordinated Universal Time) — Sat Jan 01 2000 00:00:00 GMT+0000 (Coordinated Universal Time)