
Wanzhu Zhao
Duquesne University Pittsburgh PA Research Assistant January 2016 - May 2020 1. Developed an analytical method using Lucifer Yellow to... | United States
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Wanzhu Zhao’s Location United States
Wanzhu Zhao’s Expertise Duquesne University Pittsburgh PA Research Assistant January 2016 - May 2020 1. Developed an analytical method using Lucifer Yellow to evaluate the effects of drugs on paracellular permeability of the brain endothelial cell. 2. Optimized the formulation of DNA nanoparticles using non-ionic, amphiphilic copolymers to balance the transfection efficiency and cytotoxicity in a human blood-brain barrier (BBB) model. 3. Initiated a project to isolate and analyze the bio-function of Extracellular Vesicles (EVs) from brain endothelial cells for the treatment of stroke. 4. Applied full factorial design to understand the capability of EVs to load exogenous DNA and optimize their parameters to promote the response of metabolic ability. 5. Instructed an undergraduate researcher in a parallel project using macrophage as the donor cell for the extraction of Extracellular Vesicles. 6. Applied Design of Experiment (DOE) to set up an oxygen-glucose deprivation in vitro model to mimic stroke condition. Shandong University Research Assistant 2012 - 2015 1. Detection of SALL4 gene expression in liver cancer cells and gained the understanding of HBV persistent infection in liver cancer. 2. Research on the Long-circulating Temozolomide Nanostructured Lipid Carriers.
Wanzhu Zhao’s Current Industry Astellas Pharma
Wanzhu
Zhao’s Prior Industry
Omega Therapeutics
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Astellas Pharma
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Work Experience

Astellas Pharma
Senior Research Associate
Mon Apr 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) — Present
Omega Therapeutics
Senior Research Associate
Fri Oct 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) — Thu Feb 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Omega Therapeutics
Research Associate
Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) — Fri Oct 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)